Three weeks later, all liver function tests were normal. Euthymia was maintained. What is additionally unusual is that the ultra-high dose was continued without adverse consequences for 2 months. The gradual dose up-titration reported may explain why adverse effects did not appear, as could have been expected had such a high dose been suddenly introduced.
Quetiapine was abruptly withdrawn in our patient; there were no discontinuation symptoms. This benign outcome may have resulted from replacement with oxazepam. Quetiapine is metabolized by CYP 3A4, an enzyme that has no significant polymorphisms. Therefore, his stated need for and tolerance of the high dose of 2 g nightly cannot be explained on the basis of rapid metabolism of the drug. This report probably does not illustrate quetiapine abuse,[ 5 ] an uncommon condition, because the patient used the drug for a clinical symptom and not for recreational purposes.
However, this report does indicate the easy availability, without authorization, of prescription medicine in this country. National Center for Biotechnology Information , U. This raises your risk of side effects. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:. Your doctor may start you on a lowered dosage or a different dosing schedule.
This can help keep levels of this drug from building up too much in your body. Your doctor may start you at a dosage of 50 mg daily. They may later increase it, adding 50 mg to your daily dose. The dosage may be increased at a slower rate, and a lower total daily dose may be used to lessen the risk of side effects. It has not been confirmed that quetiapine is safe and effective to use for this purpose in children younger than 13 years.
This medication has not been studied in children to use for this purpose. It should not be used in children younger than 18 years. Your doctor may start you on a lowered dose or a different dosing schedule.
The dosage will then need to be increased according to the dosage schedule from when you first started the medication. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages.
Always speak with your doctor or pharmacist about dosages that are right for you. Quetiapine oral tablet is used for long-term treatment. If you stop taking quetiapine suddenly, you may also have trouble sleeping or trouble staying asleep, or have nausea or vomiting.
For this drug to work well, a certain amount needs to be in your body at all times. If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include:. But if your symptoms are severe, call or go to the nearest emergency room right away. What to do if you miss a dose: Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose.
Never try to catch up by taking two doses at once. This could result in dangerous side effects. A prescription for this medication is refillable.
You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription. Quetiapine can make your body less able to manage your temperature. This can cause your temperature to increase too much, leading to a condition called hyperthermia.
Symptoms can include hot skin, excessive sweating, fast heartbeat, rapid breathing, and even seizures. To help prevent this, do the following during your treatment with this drug:. You and your doctor should monitor certain health issues. This can help make sure you stay safe while taking this drug. These issues include:. You may need to have blood tests from time to time to check your blood sugar and cholesterol levels.
The cost of these tests will depend on your insurance coverage. Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.
Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. This medicine may temporarily affect fertility your ability to have children in women.
Get emergency medical help if you have signs of an allergic reaction hives, difficult breathing, swelling in your face or throat or a severe skin reaction fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling. Report any new or worsening symptoms to your doctor , such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive mentally or physically , more depressed, or have thoughts about suicide or hurting yourself.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Avoid becoming overheated or dehydrated during exercise and in hot weather. You may be more prone to heat stroke. Use Quetiapine Seroquel exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. High doses or long-term use of quetiapine can cause a serious movement disorder that may not be reversible.
The longer you use quetiapine, the more likely you are to develop this disorder, especially if you are an older adult. Symptoms of this disorder include tremors or other uncontrollable muscle movements. Quetiapine may cause you to have high blood sugar hyperglycemia. If you are diabetic, check your blood sugar levels on a regular basis. It also increases the risk of transmission of HIV and hepatitis.
Seroquel might also be abused in combination with other substances such as cocaine. Mixing prescription medications with illicit drugs has been a common practice. Some people take the mix to enhance the intoxication effects from the illicit substances and lower their adverse effects. For example, Seroquel is, dangerously, mixed with cocaine to mitigate the dysphoria effects related to cocaine withdrawal.
Injecting the drug into the veins increases the risk of developing pulmonary complications. Moreover, Seroquel can amplify the cardiovascular and arrhythmogenic properties of cocaine. The first-generation antipsychotics have a larger number of side effects. But the atypical psychotics also come with a few side effects. A person taking Seroquel will experience these effects for about six hours.
Common short-term side effects of Seroquel can include:. Moreover, mixing Seroquel with alcohol comes with another set of side effects. Drinking alcohol while taking the antipsychotic can worsen the side effects of the drug and lead to:. The increase in Seroquel prescriptions has led to a rise in overdoses and problems with dependence. Although the drug has positive effects for people with mental illness, recreational use is dangerous.
Injecting Seroquel has many risks associated with it, including increased risk for HIV and hepatitis transmission. Seroquel blocks histamine, muscarinic, and alpha receptors. An overdose might lead to CNS depression, tachycardia, orthostatic hypotension, or delirium.
Apart from overdosing, other life-threatening side effects include delirium, seizures, and cardiac dysrhythmias. People who have been taking Seroquel for a prolonged period and in high doses will experience withdrawal symptoms when they stop. The most common side effects might include:.
The best method for getting clean is entering a substance abuse rehab center and undergoing detox, where a team of medical professionals can care for the person in recovery and attend to their needs.
Regular use of Seroquel for a long period of time can lead to a discontinuation syndrome. Antipsychotic discontinuation syndrome is the set of symptoms that may happen when a person:. They tend to be the most severe one week after stopping and fade away after that.
The withdrawal symptoms of Seroquel vary significantly from person to person. They depend on the doses taken, the period of time, and the method of use. For example, a person who has been taking low doses of the drug might experience minimal withdrawal symptoms that might last a week or two.
If the person has been taking higher doses for a longer time, the symptoms might be more severe. The best treatment involves tapering the dose slowly under the supervision of a medical professional. Gradual withdrawal over a period of one to two weeks is recommended. In some people, addiction is the result of an underlying mental health issue. In others, addiction develops first, and mental health symptoms appear later. Sometimes, mental health symptoms may be worsened by drug use.
Although there is no one cause for addiction, a mental health issue may increase the likelihood of developing an addiction and vice versa. People who are suffering from an addiction and a mental health problem should seek treatment for a co-occurring disorder. Many rehab centers offer an integrated approach to co-occurring disorder treatment.
Patients receive all the medical, therapeutic, and holistic care they need to heal mentally, physically, emotionally, and spiritually. Staff members at these treatment centers have specialized training and qualifications for dual diagnosis treatment. They possess the knowledge and experience to help patients achieve long-term health. A person suffering from an addiction will experience a range of withdrawal symptoms when they stop taking the drug.
This is known as the detox period, and it may last a few days or a couple of weeks. These withdrawal symptoms can be uncomfortable, harmful, and even life-threatening, and medical detox at a rehab center is recommended. People who enter a medical detox facility can withdraw from drugs safely in a comfortable and secure environment. Inpatient care lasts anywhere from 21 days to several months. Patients will live on-site and attend a wide range of activities, including:. However, all types of centers have the same focus, and that is to help the patient learn healthier habits, attitudes, and behaviors.
Outpatient care is intended for people who are suffering from a milder form of addiction. A person receiving outpatient treatment lives off-site but comes to the rehab center for on-site meetings.
Similar to inpatient care, the patient participates in step meetings and one-on-one therapy sessions. Depending on the rehab center, they might also attend holistic classes such as meditation and yoga. The purpose of an aftercare plan is to help patients maintain their sobriety, find purpose in life, and create healthy relationships with themselves, friends, and family.
Although each person receives a customized plan, some common components of a typical aftercare treatment plan include:. Participation in a step or alternative support group. Seroquel belongs to the class of drugs known as atypical antipsychotics. The drugs were initially invented as a safer alternative to first-generation antipsychotics. However, recent studies and reports suggest an alarming increase in their off-label use.
Seroquel has been named as the most commonly abused atypical antipsychotic. Seroquel abuse is related to its potent sedative effect rather than its euphoric effects. Ongoing recovery efforts, including aftercare, are also critical for a successful and long-term recovery.
This information should not replace a visit to a doctor or treatment center. If you are concerned that you or your loved one might be suffering from Seroquel addiction, ask for professional help today. Verify Your Benefits. Contact Us. Call Us Now: Our Facility.
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